Prime 95B is the Scientific CMOS with extreme sensitivity using high Quantum Efficiency (QE) Backside Illumination (BSI), a first for Scientific CMOS cameras. The 95B’s sensor converts up to 95% of incident photons into a measurable signal. Unlike microlens approaches to increasing QE, which lose effectiveness as objective magnification is increased, Prime 95B’s BSI sensor brings light into the pixel photodiode from behind, avoiding structures that reflect or absorb light. When combined with large 11μm pixels, Prime 95B can deliver over 300% more signal than other sCMOS cameras at 100X magnification.
More importantly, Prime 95B outperforms EMCCD cameras—with no excess noise that negates the benefit of using a high QE sensor, and additional limitations from EM gain calibration, stability, expense, and sensor lifetime With a true 16-bit dynamic range, Prime 95B easily accomplishes what EMCCD can not—detect weak and bright signals within the same image with photon-noise limited performance.
The extreme sensitivity not only allows fainter signals to be detected, it provides the flexibility to increase frame rates, or turn down the excitation intensity to reduce cellular photo-damage. Yet Prime 95B maintains the same high frame rates, field-of-view and extremely low read noise that has made sCMOS so popular for live-cell imaging.
The back-illuminated Kinetix Scientific CMOS (sCMOS) camera delivers the fastest speed and the largest field of view with the most balanced pixel size and near perfect 95% quantum efficiency.
Add the MultiSplit from Cairn Research Ltd to allow simultaneous four-channel imaging，and each field of view has a 13mm diagonal.
The Prime BSI Express Scientific CMOS (sCMOS) is designed on a compact platform optimized for integration and delivers the perfect balance between high resolution imaging and sensitivity with an optimized pixel design, USB 3.2 Gen 2 connectivity and near perfect 95% Quantum Efficiency to maximize signal detection.
The Prime BSI Express combines 95% quantum efficiency with the low 1.0 e- read noise CMS mode to deliver the most sensitive camera based on sCMOS technology at over 40 frames per second.
The Prime BSI Express features 6.5 µm pixels, the accepted standard for most live cell applications.This pixel size provides highly detailed images across the imaging plane and is most suitable for the broadest range of magnifications.
The Prime BSI Express features Pattern Noise Reduction Technology and Correlated Noise Reduction Technology to ensure that it delivers clean, pattern-free images with minimal pixel defects, delivering improved image quality in low light conditions.
The back-illuminated Kinetix Scientific CMOS (sCMOS) camera delivers the fastest speed and the largest field of view with the most balanced pixel size and near perfect 95% quantum efficiency.
Add the MultiSplit from Cairn Research Ltd to allow simultaneous four-channel imaging，and each field of view has a 13mm diagonal.
The Prime BSI Express Scientific CMOS (sCMOS) is designed on a compact platform optimized for integration and delivers the perfect balance between high resolution imaging and sensitivity with an optimized pixel design, USB 3.2 Gen 2 connectivity and near perfect 95% Quantum Efficiency to maximize signal detection.
The Prime BSI Express combines 95% quantum efficiency with the low 1.0 e- read noise CMS mode to deliver the most sensitive camera based on sCMOS technology at over 40 frames per second.
The Prime BSI Express features 6.5 µm pixels, the accepted standard for most live cell applications.This pixel size provides highly detailed images across the imaging plane and is most suitable for the broadest range of magnifications.
The Prime BSI Express features Pattern Noise Reduction Technology and Correlated Noise Reduction Technology to ensure that it delivers clean, pattern-free images with minimal pixel defects, delivering improved image quality in low light conditions.
